High methionine diet in skeletal muscle remodeling: Epigenetic mechanism of homocysteine mediated growth retardation

High methionine diet in skeletal muscle remodeling: Epigenetic mechanism of homocysteine mediated growth retardation

Epigenetic DNA methylation is essential for gene-imprinting/off-printing making certain epigenetic reminiscence however generates copious homocysteine (Hcy) unequivocally. That’s the reason throughout being pregnant moms are advisable ‘folic acid’ to keep away from birth-defects due to elevated Hcy ranges (hyperhomocysteinemia; HHcy). Kids born with HHcy have musculoskeletal abnormalities/development retardation. We give attention to gut-dysbiotic microbiome implication […]

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The Relationship Between Blood Hypoxia-Inducible Factor-1α, Fetuin-A, Fibrinogen, Homocysteine, and Amputation Level

The Relationship Between Blood Hypoxia-Inducible Factor-1α, Fetuin-A, Fibrinogen, Homocysteine, and Amputation Level

Decreased life expectancy has resulted from an elevated incidence of continual issues in sufferers with diabetes. The diabetic foot is one in every of these issues and usually presents along with diabetic neuropathy and vascular insufficiency. Hypoxia-inducible factor-1α (HIF-1α) is vital in creating the variation response to hypoxia and facilitates therapeutic by regulation of keratinocyte […]

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An Ir(III) complex capable of discriminating homocysteine from cysteine and glutathione with luminescent signal and imaging studies

An Ir(III) complex capable of discriminating homocysteine from cysteine and glutathione with luminescent signal and imaging studies

A brand new cationic Ir(III) complicated with aldehyde and amino teams was synthesized and characterised. The Ir(III) complicated has wealthy photophysical properties. The response of the aldehyde group within the Ir(III) complicated with homocysteine (Hcy) afforded thiazinane derivatives which resulted in apparent adjustments within the luminescence spectra. After addition of Hcy to the Ir(III) complicated […]

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