The Relationship Between Blood Hypoxia-Inducible Factor-1α, Fetuin-A, Fibrinogen, Homocysteine, and Amputation Level

The Relationship Between Blood Hypoxia-Inducible Factor-1α, Fetuin-A, Fibrinogen, Homocysteine, and Amputation Level

Decreased life expectancy has resulted from an elevated incidence of continual issues in sufferers with diabetes. The diabetic foot is one in every of these issues and usually presents along with diabetic neuropathy and vascular insufficiency. Hypoxia-inducible factor-1α (HIF-1α) is vital in creating the variation response to hypoxia and facilitates therapeutic by regulation of keratinocyte migration and epithelium restoration in wounds.

Fetuin-A is a transporter protein that’s synthesized within the liver and inhibits vascular and ectopic calcifications. It has been noticed that altered fetuin-A is related to peripheral artery illness by vascular calcification and is related to irritation and metabolic syndrome incidence in diabetic sufferers.

Fibrinogen is an acute-phase reactant and has a significant position in homeostasis, tissue restore, and wound therapeutic. Elevated fibrinogen blood degree is likely one of the components that facilitates the hypercoagulability in diabetics. Homocysteine has atherogenic options and causes vascular toxicity by enhancing low-density lipoprotein oxidation.

We evaluated the affiliation of serum HIF-1α, fetuin-A, fibrinogen, and homocysteine ranges with amputation in 31 sufferers identified with diabetes mellitus. In keeping with our analysis, a detrimental correlation was decided between fetuin-A and amputation degree, which was statistically vital. Sadly, there was no vital correlation between HIF-1α, fibrinogen, homocysteine, and amputation degree (P > .05). In consequence, it was advised that vascular calcification resulting from fetuin-A deficiency could also be vital within the diabetic foot pathogenesis and that fetuin-A ranges could also be a predictor for amputation degree.

Elevated Homocysteine after Elevated Propionylcarnitine or Low Methionine in New child Screening Is Extremely Predictive for Low Vitamin B12 and Holo-Transcobalamin Ranges in Newborns

Early diagnostics and remedy of vitamin B12 deficiency (B12D) in infants, primarily maternally conditioned, is essential in stopping potential developmental delay and neurological deficits. At present, B12D is never listed in common new child screening panels and principally considered an incidental discovering.
The intention of this research was to guage a focused new child screening technique for detection of suspected B12D. A call technique based mostly on the first parameters propionylcarnitine and methionine for number of samples to be analyzed for whole homocysteine by mass spectrometry was established. Subsequently, 93,116 newborns had been initially screened. Concentrations of vitamin B12 and holotranscobalamin in serum had been obtained from medical follow-up analyses of recalled newborns.
Furthermore, a particularly delicate mass spectrometric technique to quantify methylmalonic acid from the dried blood spots was developed. Total, 0.15% of newborns had been screened optimistic for suspected B12D, of which 64% had vitamin B12 concentrations beneath 148 pM. We additionally decided a cutoff worth for methylmalonic acid in dried blood spots indicative for B12D in infants.
Total, we calculated a prevalence of 92/100,000 for suspected B12D within the Austrian newborns. In conclusion, we current a screening algorithm together with second-tier measurement of whole homocysteine that enables detection of low B12 serum concentrations with a excessive detection price and low false-positive price.
Twenty-four grownup male Sprague-Dawley rats had been randomly allotted into 4 teams and handled every day for 28 days as follows: group I: management;group II: ginger (1g/kg/day ginger extract by oral gavage); group III: ethanol (4g/kg/day ethanol by oral gavage) and group IV: ginger+ethanol. On the finish of the experimental interval, eye tissue sera had been used for dedication of various parameters. Moreover, in vitro antioxidant potential and whole phenol content material of ginger extract had been decided.
 The Relationship Between Blood Hypoxia-Inducible Factor-1α, Fetuin-A, Fibrinogen, Homocysteine, and Amputation Level
The Relationship Between Blood Hypoxia-Inducible Factor-1α, Fetuin-A, Fibrinogen, Homocysteine, and Amputation Level

DNA methyltransferase-1 inactivation of androgen receptor axis triggers homocysteine induced cardiac fibroblast autophagy in diabetic cardiac fibrosis

Diabetic cardiac fibrosis is likely one of the important pathological manifestations of diabetic cardiomyopathy (DCM). Cardiac fibroblast autophagy performs vital roles in diabetic cardiac fibrosis, nevertheless, the underlying mechanism of cardiac fibroblast autophagy and diabetic cardiac fibrosis nonetheless largely unknown.
The intention of the research was to research the mechanism of DNMT1 mediated DNA methylation alterations management cardiac fibroblast autophagy in diabetic cardiac fibrosis. We employed streptozotocin (STZ)-induced rats DCM, DCM affected person and Hcy induced cardiac fibroblast autophagy.
Coronary heart tissue sections had been stained with H&E, Sirius Purple and Masson’s trichrome stain. The expression of DNMT1, AR, Collagen genes mRNA was detected by qRT-PCR. MSP and BSP detected the methylation standing of the AR promoter. The expression of DNMT1, AR, Collagen and autophagy-related proteins had been detected by Western blotting, Immunofluorescence, Immunohistochemistry. Achieve and loss operate of AR and DNMT1 in cardiac fibroblast was analyzed. DNMT1 inhibition or knockdown elevated the expression of AR in cardiac fibroblast.

Pig Homocysteine ELISA kit

E07H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Homocysteine ELISA kit

E07H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Homocysteine ELISA kit

E08H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Homocysteine ELISA kit

E08H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Homocysteine ELISA kit

E08H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

HCY(Homocysteine) ELISA Kit

EKF58404-48T 48T
EUR 396.9

HCY(Homocysteine) ELISA Kit

EKF58404-5x96T 5x96T
EUR 2693.25

HCY(Homocysteine) ELISA Kit

EKF58404-96T 96T
EUR 567

Rat Homocysteine ELISA kit

E01A13873 96T
EUR 700
Description: ELISA

Rat Homocysteine ELISA Kit

MBS109432-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Homocysteine ELISA Kit

MBS109432-48StripWells 48-Strip-Wells
EUR 550

Rat Homocysteine ELISA Kit

MBS109432-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Homocysteine ELISA Kit

MBS109432-96StripWells 96-Strip-Wells
EUR 765

Rat Homocysteine ELISA Kit

EF018158 96tests
EUR 566

HCY(Homocysteine) ELISA Kit

EU0197 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: General;Sensitivity: 4.688pmol/ml

HCy(Homocysteine) ELISA Kit

ELK8121-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

HCy(Homocysteine) ELISA Kit

ELK8121-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat homocysteine ELISA kit

QY-E11727 96T
EUR 448.8

Rat homocysteine ELISA Kit

MBS7254595-10x96StripWells 10x96-Strip-Wells
EUR 5685

Rat homocysteine ELISA Kit

MBS7254595-48StripWells 48-Strip-Wells
EUR 485

Rat homocysteine ELISA Kit

MBS7254595-5x96StripWells 5x96-Strip-Wells
EUR 3020

Rat homocysteine ELISA Kit

MBS7254595-96StripWells 96-Strip-Wells
EUR 690

Rat Homocysteine ELISA Kit

MBS7255240-10x96StripWells 10x96-Strip-Wells
EUR 5685

Rat Homocysteine ELISA Kit

MBS7255240-48StripWells 48-Strip-Wells
EUR 485

Rat Homocysteine ELISA Kit

MBS7255240-5x96StripWells 5x96-Strip-Wells
EUR 3020

Rat Homocysteine ELISA Kit

MBS7255240-96StripWells 96-Strip-Wells
EUR 690

HCY (Homocysteine) ELISA Kit

MBS7607153-10x96StripWells 10x96-Strip-Wells
EUR 3900

HCY (Homocysteine) ELISA Kit

MBS7607153-48StripWells 48-Strip-Wells
EUR 340

HCY (Homocysteine) ELISA Kit

MBS7607153-5x96StripWells 5x96-Strip-Wells
EUR 2045

HCY (Homocysteine) ELISA Kit

MBS7607153-96StripWells 96-Strip-Wells
EUR 455

Goat Homocysteine ELISA kit

E01A48781 96T
EUR 700
Description: ELISA

Goat Homocysteine ELISA kit

E06H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Homocysteine ELISA kit

E06H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Homocysteine ELISA kit

E06H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Homocysteine ELISA Kit

MBS7258770-10x96StripWells 10x96-Strip-Wells
EUR 5685

Goat Homocysteine ELISA Kit

MBS7258770-48StripWells 48-Strip-Wells
EUR 485

Goat Homocysteine ELISA Kit

MBS7258770-5x96StripWells 5x96-Strip-Wells
EUR 3020

Goat Homocysteine ELISA Kit

MBS7258770-96StripWells 96-Strip-Wells
EUR 690

Human Homocysteine ELISA kit

E01A5119 96T
EUR 700
Description: ELISA

Mouse Homocysteine ELISA kit

E01A22613 96T
EUR 700
Description: ELISA

Mouse Homocysteine ELISA kit

E03H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Homocysteine ELISA kit

E03H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Homocysteine ELISA kit

E03H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Homocysteine ELISA kit

E01H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Homocysteine ELISA kit

E01H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Homocysteine ELISA kit

E01H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Sheep Homocysteine ELISA kit

E01A101074 96T
EUR 700
Description: ELISA

Human Homocysteine ELISA Kit

ELA-E0772h 96tests
EUR 696

Human Homocysteine ELISA Kit

MBS7252797-10x96StripWells 10x96-Strip-Wells
EUR 5685

Human Homocysteine ELISA Kit

MBS7252797-48StripWells 48-Strip-Wells
EUR 485

Human Homocysteine ELISA Kit

MBS7252797-5x96StripWells 5x96-Strip-Wells
EUR 3020

Human Homocysteine ELISA Kit

MBS7252797-96StripWells 96-Strip-Wells
EUR 690

Mouse Homocysteine ELISA Kit

MBS7256088-10x96StripWells 10x96-Strip-Wells
EUR 5685

Mouse Homocysteine ELISA Kit

MBS7256088-48StripWells 48-Strip-Wells
EUR 485

Mouse Homocysteine ELISA Kit

MBS7256088-5x96StripWells 5x96-Strip-Wells
EUR 3020

Mouse Homocysteine ELISA Kit

MBS7256088-96StripWells 96-Strip-Wells
EUR 690

Sheep Homocysteine ELISA Kit

MBS7266163-10x96StripWells 10x96-Strip-Wells
EUR 5685

Sheep Homocysteine ELISA Kit

MBS7266163-48StripWells 48-Strip-Wells
EUR 485

Sheep Homocysteine ELISA Kit

MBS7266163-5x96StripWells 5x96-Strip-Wells
EUR 3020

Sheep Homocysteine ELISA Kit

MBS7266163-96StripWells 96-Strip-Wells
EUR 690

Mouse Homocysteine ELISA Kit

MBS760065-10x96StripWells 10x96-Strip-Wells
EUR 3900

Mouse Homocysteine ELISA Kit

MBS760065-48StripWells 48-Strip-Wells
EUR 340

Mouse Homocysteine ELISA Kit

MBS760065-5x96StripWells 5x96-Strip-Wells
EUR 2045

Mouse Homocysteine ELISA Kit

MBS760065-96StripWells 96-Strip-Wells
EUR 455

Rabbit Homocysteine ELISA kit

E01A31349 96T
EUR 700
Description: ELISA

Canine Homocysteine ELISA kit

E01A66212 96T
EUR 700
Description: ELISA

Rabbit Homocysteine ELISA kit

E04H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Homocysteine ELISA kit

E04H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Homocysteine ELISA kit

E04H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Bovine Homocysteine ELISA kit

E01A83646 96T
EUR 700
Description: ELISA

Monkey Homocysteine ELISA kit

E01A74928 96T
EUR 700
Description: ELISA

Monkey Homocysteine ELISA kit

E09H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Homocysteine ELISA kit

E09H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Homocysteine ELISA kit

E09H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Homocysteine ELISA Kit

MBS7256926-10x96StripWells 10x96-Strip-Wells
EUR 5685

Rabbit Homocysteine ELISA Kit

MBS7256926-48StripWells 48-Strip-Wells
EUR 485

Rabbit Homocysteine ELISA Kit

MBS7256926-5x96StripWells 5x96-Strip-Wells
EUR 3020

Rabbit Homocysteine ELISA Kit

MBS7256926-96StripWells 96-Strip-Wells
EUR 690

Monkey Homocysteine ELISA Kit

MBS7262835-10x96StripWells 10x96-Strip-Wells
EUR 5685

Monkey Homocysteine ELISA Kit

MBS7262835-48StripWells 48-Strip-Wells
EUR 485

Monkey Homocysteine ELISA Kit

MBS7262835-5x96StripWells 5x96-Strip-Wells
EUR 3020

Monkey Homocysteine ELISA Kit

MBS7262835-96StripWells 96-Strip-Wells
EUR 690

Bovine Homocysteine ELISA Kit

MBS7263757-10x96StripWells 10x96-Strip-Wells
EUR 5685

Bovine Homocysteine ELISA Kit

MBS7263757-48StripWells 48-Strip-Wells
EUR 485

Bovine Homocysteine ELISA Kit

MBS7263757-5x96StripWells 5x96-Strip-Wells
EUR 3020

Bovine Homocysteine ELISA Kit

MBS7263757-96StripWells 96-Strip-Wells
EUR 690

Canine Homocysteine ELISA Kit

MBS7261894-10x96StripWells 10x96-Strip-Wells
EUR 5685

Canine Homocysteine ELISA Kit

MBS7261894-48StripWells 48-Strip-Wells
EUR 485

Canine Homocysteine ELISA Kit

MBS7261894-5x96StripWells 5x96-Strip-Wells
EUR 3020

Canine Homocysteine ELISA Kit

MBS7261894-96StripWells 96-Strip-Wells
EUR 690

Porcine Homocysteine ELISA kit

E01A57499 96T
EUR 700
Description: ELISA

Chicken Homocysteine ELISA kit

E01A92368 96T
EUR 700
Description: ELISA

Porcine Homocysteine ELISA Kit

MBS7260942-10x96StripWells 10x96-Strip-Wells
EUR 5685

Porcine Homocysteine ELISA Kit

MBS7260942-48StripWells 48-Strip-Wells
EUR 485

Porcine Homocysteine ELISA Kit

MBS7260942-5x96StripWells 5x96-Strip-Wells
EUR 3020

Porcine Homocysteine ELISA Kit

MBS7260942-96StripWells 96-Strip-Wells
EUR 690

Chicken Homocysteine ELISA Kit

MBS7264808-10x96StripWells 10x96-Strip-Wells
EUR 5685

Chicken Homocysteine ELISA Kit

MBS7264808-48StripWells 48-Strip-Wells
EUR 485

Chicken Homocysteine ELISA Kit

MBS7264808-5x96StripWells 5x96-Strip-Wells
EUR 3020

Chicken Homocysteine ELISA Kit

MBS7264808-96StripWells 96-Strip-Wells
EUR 690

General Homocysteine ELISA Kit

MBS9426073-5x96Tests 5x96Tests
EUR 3065

General Homocysteine ELISA Kit

MBS9426073-96Tests 96Tests
EUR 670

General Homocysteine ELISA Kit

MBS2883009-10x96StripWells 10x96-Strip-Wells
EUR 4630

General Homocysteine ELISA Kit

MBS2883009-48StripWells 48-Strip-Wells
EUR 440

General Homocysteine ELISA Kit

MBS2883009-5x96StripWells 5x96-Strip-Wells
EUR 2480

General Homocysteine ELISA Kit

MBS2883009-96StripWells 96-Strip-Wells
EUR 580

Homocysteine ELISA Kit (OKEH02557)

OKEH02557 96 Wells
EUR 934.8
Description: Description of target: Homocysteine is a non-protein amino acid with the formula HSCH2CH2CH(NH2)CO2H. It is a homologue of the amino acid cysteine, differing by an additional methylene (-CH2-) group. It is biosynthesized from methionine by the removal of its terminal Cε methyl group. Homocysteine can be recycled into methionine or converted into cysteine with the aid of B-vitamins. While detection of high levels of homocysteine has been linked to cardiovascular disease, lowering homocysteine levels may not improve outcomes.;Species reactivity: All;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.38 ng/mL

Rat HCY(Homocysteine) ELISA Kit

EKF57965-48T 48T
EUR 396.9

Rat HCY(Homocysteine) ELISA Kit

EKF57965-5x96T 5x96T
EUR 2693.25

Rat HCY(Homocysteine) ELISA Kit

EKF57965-96T 96T
EUR 567

Rat HCY(Homocysteine) ELISA Kit

ER1509 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Rattus;Sensitivity: 4.688pmol/ml

Human HCY(Homocysteine) ELISA Kit

EH4011 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688pmol/ml

Human HCY(Homocysteine) ELISA Kit

EKF58017-48T 48T
EUR 396.9

Human HCY(Homocysteine) ELISA Kit

EKF58017-5x96T 5x96T
EUR 2693.25

Human HCY(Homocysteine) ELISA Kit

EKF58017-96T 96T
EUR 567

Mouse HCY(Homocysteine) ELISA Kit

EKF59110-48T 48T
EUR 396.9

Mouse HCY(Homocysteine) ELISA Kit

EKF59110-5x96T 5x96T
EUR 2693.25

Mouse HCY(Homocysteine) ELISA Kit

EKF59110-96T 96T
EUR 567

Human HCy(Homocysteine) ELISA Kit

ELK8987-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

Human HCy(Homocysteine) ELISA Kit

ELK8987-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse HCY(Homocysteine) ELISA Kit

EM1109 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 4.688pmol/ml

Mouse HCy(Homocysteine) ELISA Kit

ELK8718-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Mouse HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse HCy(Homocysteine) ELISA Kit

ELK8718-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Mouse HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse HCy (Homocysteine) ELISA Kit

MBS8807642-10x96StripWells 10x96-Strip-Wells
EUR 3130

Mouse HCy (Homocysteine) ELISA Kit

MBS8807642-48StripWells 48-Strip-Wells
EUR 315

Mouse HCy (Homocysteine) ELISA Kit

MBS8807642-5x96StripWells 5x96-Strip-Wells
EUR 1710

Mouse HCy (Homocysteine) ELISA Kit

MBS8807642-96StripWells 96-Strip-Wells
EUR 385

Human HCy (Homocysteine) ELISA Kit

MBS8807910-10x96StripWells 10x96-Strip-Wells
EUR 3130

Human HCy (Homocysteine) ELISA Kit

MBS8807910-48StripWells 48-Strip-Wells
EUR 315

Human HCy (Homocysteine) ELISA Kit

MBS8807910-5x96StripWells 5x96-Strip-Wells
EUR 1710

Human HCy (Homocysteine) ELISA Kit

MBS8807910-96StripWells 96-Strip-Wells
EUR 385

Homocysteine (HCY) ELISA Kit

abx576699-96tests 96 tests
EUR 801.6

Homocysteine (HCY) ELISA Kit

20-abx156751
  • Ask for price
  • Ask for price
  • Ask for price
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Homocysteine (HCy) ELISA Kit

DLR-HCy-Ge-48T 48T
EUR 694.8
Description: A competitive inhibition quantitative ELISA assay kit for detection of Homocysteine (HCy) in samples from serum, plasma, tissue homogenates or other biological fluids.

Homocysteine (HCy) ELISA Kit

DLR-HCy-Ge-96T 96T
EUR 910.8
Description: A competitive inhibition quantitative ELISA assay kit for detection of Homocysteine (HCy) in samples from serum, plasma, tissue homogenates or other biological fluids.

Homocysteine (HCy) ELISA Kit

EKU12220-48T 48T
EUR 777.14

Homocysteine (HCy) ELISA Kit

EKU12220-5x96T 5x96T
EUR 5273.45

Homocysteine (HCy) ELISA Kit

EKU12220-96T 96T
EUR 1110.2

Homocysteine (HCy) ELISA Kit

EKN53330-48T 48T
EUR 483.56

Homocysteine (HCy) ELISA Kit

EKN53330-5x96T 5x96T
EUR 3281.3

Homocysteine (HCy) ELISA Kit

EKN53330-96T 96T
EUR 690.8

Homocysteine (HCy) ELISA Kit

EKU08750-48T 48T
EUR 647.92

Homocysteine (HCy) ELISA Kit

EKU08750-5x96T 5x96T
EUR 4396.6

Homocysteine (HCy) ELISA Kit

EKU08750-96T 96T
EUR 925.6

Homocysteine (HCy) ELISA Kit

EKN49861-48T 48T
EUR 403.06

Homocysteine (HCy) ELISA Kit

EKN49861-5x96T 5x96T
EUR 2735.05

Homocysteine (HCy) ELISA Kit

EKN49861-96T 96T
EUR 575.8

Homocysteine (HCY) ELISA Kit

abx156751-100g 100 µg
EUR 6412.5

Homocysteine (HCY) ELISA Kit

abx156751-10g 10 µg
EUR 712.5

Homocysteine (HCY) ELISA Kit

abx156751-50g 50 µg
EUR 3387.5

Homocysteine (HCY) ELISA Kit

abx576699-296tests 2 × 96 tests
EUR 687.5

Guinea Pig Homocysteine ELISA kit

E01A40062 96T
EUR 700
Description: ELISA

Guinea pig Homocysteine ELISA kit

E05H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Homocysteine ELISA kit

E05H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Homocysteine ELISA kit

E05H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig Homocysteine ELISA Kit

MBS7257813-10x96StripWells 10x96-Strip-Wells
EUR 5685

Guinea Pig Homocysteine ELISA Kit

MBS7257813-48StripWells 48-Strip-Wells
EUR 485

Guinea Pig Homocysteine ELISA Kit

MBS7257813-5x96StripWells 5x96-Strip-Wells
EUR 3020

Guinea Pig Homocysteine ELISA Kit

MBS7257813-96StripWells 96-Strip-Wells
EUR 690

General Hcy/ Homocysteine ELISA Kit

E0037Ge 1 Kit
EUR 630

General Homocysteine ELISA Kit (HCy)

RK00671 96 Tests
EUR 625.2

General Hcy / Homocysteine ELISA Kit

E0772Ge 96T
EUR 676

General HCy (Homocysteine) ELISA Kit

MBS8807090-10x96StripWells 10x96-Strip-Wells
EUR 3130

General HCy (Homocysteine) ELISA Kit

MBS8807090-48StripWells 48-Strip-Wells
EUR 315
Moreover, we discovered that AR negatively regulation of Hcy induced cardiac fibroblast autophagy. We demonstrated that DNMT1 enhances cardiac fibroblast autophagy in diabetic cardiac fibrosis by inhibiting AR axis. In conclusion, our outcomes present new perception into the DNMT1 inactivation of AR axis triggers cardiac fibroblast autophagy in diabetic cardiac fibrosis.

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