N-Methyl-D-aspartate receptor activation, novel mechanism of homocysteine-induced blood-retinal barrier dysfunction

Elevated ranges of amino acid homocysteine (Hcy) acknowledged as hyperhomocysteinemia (HHcy) was reported in a number of human visible issues, akin to diabetic retinopathy (DR) and age-related macular degeneration (AMD). Breakdown of blood-retinal barrier (BRB) is concomitant with imaginative and prescient loss in DR and AMD. We beforehand reported that HHcy alters BRB. Right here, we examined the speculation that HHcy alters BRB through activation of N-methyl-D-aspartate receptor (NMDAR). Human retinal endothelial cells subjected to excessive stage of Hcy and mouse mannequin of HHcy had been used. We injected Hcy intravitreal and used a mouse mannequin of HHcy that lacks cystathionine-β-synthase (CBS).

RT-PCR, western blot, and immunofluorescence confirmed that retinal endothelial cells (RECs) specific NMDAR on the gene and protein ranges each in vitro and in vivo and this was elevated by HHcy. We assessed BRB operate and retinal morphology utilizing fluorescein angiogram and optical coherence tomography (OCT) beneath HHcy with and with out pharmacological inhibition of NMDAR by (MK801) or in mice missing endothelial NMDAR (NMDARE-/- mouse). Moreover, retinal albumin leakage and tight junction proteins ZO-1 and occludin had been assessed by western blotting evaluation.

Inhibition or elimination of NMDAR was capable of enhance the altered retinal hyperpermeability and morphology beneath HHcy as indicated by vital lower in retinal albumin leakage and restoration of tight junction proteins ZO-1 and occludin. Our findings underscore a possible function for endothelial NMDAR in mediating Hcy-induced breakdown of BRB and subsequently as a possible therapeutic goal in retinal illnesses related to HHcy akin to DR and AMD. KEY MESSAGES: • Elevated ranges of homocysteine (Hcy) are outlined as hyperhomocysteinemia (HHcy). • HHcy is implicated in diabetic retinopathy and age-related macular degeneration. • HHcy alters BRB through activation of N-methyl-D-aspartate receptor.

Homocysteine is a vital intermediate product of biochemical reactions that’s current in numerous tissues of the human physique. Homocysteine could also be related to the event and development of Parkinson’s illness. Plasma homocysteine ranges in sufferers with Parkinson’s illness are elevated in comparison with these of wholesome people.

Excessive homocysteine drives PD growth and development whereas aggregating the medical signs of PD sufferers. The connection between PD and homocysteine entails a number of pathways, together with nerve cell apoptosis, oxidative stress, and DNA harm. That is essential for explaining how excessive homocysteine drives the PD procession. Elevated homocysteine stage throughout PD growth and development presents a brand new technique for the analysis and therapy of this illness.

 

Activation of arginase II by uneven dimethylarginine and homocysteine in hypertensive rats induced by hypoxia: a brand new mannequin of nitric oxide synthesis regulation in hypertensive processes?

 

In recent times, the rise in blood strain at excessive altitudes has change into an attention-grabbing matter amongst high-altitude researchers. In our animal research utilizing Wistar rats, we noticed the existence of two rat populations that exhibit differential physiological responses throughout hypoxic publicity.

These rats had been labeled as hypoxia-induced hypertensive rats and nonhypertensive rats. A lower in nitric oxide ranges was reported in numerous hypertension fashions related to elevated concentrations of uneven dimethylarginine (ADMA) and homocysteine, and we not too long ago described a rise in arginase kind II expression beneath hypoxia.

ADMA and homocysteine lower nitric oxide (NO) bioavailability; nevertheless, whether or not ADMA and homocysteine have a regulatory impact on arginase exercise and subsequently regulate one other NO synthesis pathway is unknown. Due to this fact, the goal of this examine was to measure basal ADMA and homocysteine ranges in hypoxia-induced hypertensive rats and consider their impact on arginase II exercise. Our outcomes point out that hypoxia-induced hypertensive rats introduced decrease nitric oxide concentrations than nonhypertensive rats, related to greater concentrations of homocysteine and ADMA.

Hypoxia-induced hypertensive rats additionally introduced decrease dimethylarginine dimethylaminohydrolase-2 and cystathionine β-synthase ranges, which might clarify the excessive ADMA and homocysteine ranges. As well as, we noticed that each homocysteine and ADMA had a major impact on arginase II activation within the hypertensive rats. Due to this fact, we recommend that ADMA and homocysteine have twin regulatory results on NO synthesis.

The previous has an inhibitory impact on eNOS, and the latter has a secondary activating impact on arginase II. We suggest that arginase II is activated by AMDA and homocysteine in hypoxia-induced hypertensive rats.

N-Methyl-D-aspartate receptor activation, novel mechanism of homocysteine-induced blood-retinal barrier dysfunction
N-Methyl-D-aspartate receptor activation, novel mechanism of homocysteine-induced blood-retinal barrier dysfunction

Homocysteine stage is positively and independently related to serum creatinine and urea nitrogen ranges in previous male sufferers with hypertension

A cross-sectional examine to indicate whether or not and the way serum fasting homocysteine ranges are related to renal operate modifications in sufferers with hypertension. Homocysteine ranges had been related to serum creatinine and blood urea nitrogen (BUN) ranges with coefficients of two.04 and 0.07, respectively, solely in males and impartial of confounders.
As well as, low density lipoprotein ldl cholesterol (LDL-C) ranges had been positively and left ventricular ejection fraction (LVEF) was negatively related to serum creatinine stage in males; age was positively related to serum creatinine ranges in females. Age was a typical threat issue positively related to BUN ranges in each sexes, whereas whole ldl cholesterol (TC) ranges and glycemic management had been impartial threat elements that had been positively related to BUN ranges solely in males. LDL-C ranges and LVEF had been negatively related to BUN ranges in females.

Homocysteine (OVA)

abx165754-50g 50 µg
EUR 612.5

Human Homocysteine

QY-E05856 96T
EUR 400

Homocysteine [G-BSA]

DAG3334 250ug
EUR 702

Homocysteine (HCy) (BSA)

abx169103-1ml 1 ml
EUR 700

Homocysteine ELISA Kit

E4543-100 each
EUR 966

Homocysteine Assay Kit

abx098434-Hitachi7060R160ml1R210ml1 Hitachi 7060; R1: 60ml×1 R2: 10ml×1
EUR 1243.2

Homocysteine Assay Kit

abx098434-Hitachi7170R130ml2R210ml1 Hitachi 7170; R1: 30ml×2 R2: 10ml×1
EUR 1243.2

Homocysteine Assay Kit

abx098434-Toshiba40R130ml2R210ml1 Toshiba 40; R1: 30ml×2 R2: 10ml×1
EUR 1243.2

Homocysteine Assay Kit

abx098434-UniversalR130ml2R210ml1 Universal; R1: 30ml×2 R2: 10ml×1
EUR 1243.2

Homocysteine ELISA Kit

STA-670 96 assays
EUR 838.8
Description: Homocysteine is an amino acid intermediate that is synthesized from methionine via S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH). Elevated levels of homocysteine can indicate a risk for numerous diseases, including vascular and heart disease. Our Homocysteine ELISA is designed for detection and quantitation of homocysteine in plasma, serum, lysates, or biological fluid samples. This assay is a competitive ELISA where samples and an anti-homocysteine antibody are added to a plate coated with a homocysteine conjugate. The sample and conjugate compete for antibody binding, which generates a reverse curve. Samples with high homocysteine levels will bind to most of the antibody, which gets washed away and results in a low OD, while samples with low homocysteine levels will leave more antibody available to bind to the conjugate, producing a high signal.

Homocysteine ELISA Kit

IMLHCYKT each
EUR 843
Description: Homocysteine ELISA Kit

Homocysteine ELISA Kit

ECP7876 96 Tests
EUR 646

Homocysteine Assay Kit

abx098434-100l 100 µl
EUR 575

Homocysteine Assay Kit

abx098434-1ml 1 ml Ask for price

Homocysteine Assay Kit

abx098434-200l 200 µl Ask for price

S-adenosyl homocysteine

52031 250 µL
EUR 325
Description: S-(5'-Adenosyl)-L-homocysteine (AdoHCys, SAH) is a competitive inhibitor (versus AdoMet) of DNA methyltransferases. AdoHcy is used in a variety of studies on epigenetics in hyperhomocysteinemic states. EC Number: 213-560-8

Homocysteine (HCy) Antibody

20-abx100806
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

S-adenosyl homocysteine

GWB-PS69E7 250?L Ask for price

Linearity LQ Homocysteine

K704M-5 5 x 1 mL
EUR 343

Homocysteine (HCy) Antibody

abx100806-100l 100 µl
EUR 287.5

Homocysteine (HCy) Antibody

abx100806-1ml 1 ml
EUR 850

Homocysteine (HCy) Antibody

abx100806-200l 200 µl
EUR 375

Homocysteine (HCY) CLIA Kit

20-abx490512
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Homocysteine (HCy) ELISA Kit

DLR-HCy-Ge-48T 48T
EUR 694.8
Description: A competitive inhibition quantitative ELISA assay kit for detection of Homocysteine (HCy) in samples from serum, plasma, tissue homogenates or other biological fluids.

Homocysteine (HCy) ELISA Kit

DLR-HCy-Ge-96T 96T
EUR 910.8
Description: A competitive inhibition quantitative ELISA assay kit for detection of Homocysteine (HCy) in samples from serum, plasma, tissue homogenates or other biological fluids.

Rat Homocysteine ELISA kit

E02H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Homocysteine ELISA kit

E02H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Homocysteine ELISA kit

E02H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Homocysteine ELISA kit

E08H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Homocysteine ELISA kit

E08H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Homocysteine ELISA kit

E08H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Homocysteine ELISA kit

E07H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Homocysteine ELISA kit

E07H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Homocysteine ELISA kit

E07H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

HCy(Homocysteine) ELISA Kit

ELK8121-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

HCy(Homocysteine) ELISA Kit

ELK8121-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

HCY(Homocysteine) ELISA Kit

EU0197 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: General;Sensitivity: 4.688pmol/ml

HCY(Homocysteine) ELISA Kit

EKF58404-48T 48T
EUR 396.9

HCY(Homocysteine) ELISA Kit

EKF58404-5x96T 5x96T
EUR 2693.25

HCY(Homocysteine) ELISA Kit

EKF58404-96T 96T
EUR 567

Homocysteine (HCy) ELISA Kit

EKU08750-48T 48T
EUR 647.92

Homocysteine (HCy) ELISA Kit

EKU08750-5x96T 5x96T
EUR 4396.6

Homocysteine (HCy) ELISA Kit

EKU08750-96T 96T
EUR 925.6

Homocysteine (HCy) ELISA Kit

EKU12220-48T 48T
EUR 777.14

Homocysteine (HCy) ELISA Kit

EKU12220-5x96T 5x96T
EUR 5273.45

Homocysteine (HCy) ELISA Kit

EKU12220-96T 96T
EUR 1110.2

Homocysteine (HCy) ELISA Kit

EKN53330-48T 48T
EUR 483.56

Homocysteine (HCy) ELISA Kit

EKN53330-5x96T 5x96T
EUR 3281.3

Homocysteine (HCy) ELISA Kit

EKN53330-96T 96T
EUR 690.8

Homocysteine (HCy) ELISA Kit

EKN49861-48T 48T
EUR 403.06

Homocysteine (HCy) ELISA Kit

EKN49861-5x96T 5x96T
EUR 2735.05

Homocysteine (HCy) ELISA Kit

EKN49861-96T 96T
EUR 575.8

Rat Homocysteine ELISA kit

E01A13873 96T
EUR 700
Description: ELISA

Homocysteine (HCY) ELISA Kit

abx576699-96tests 96 tests
EUR 801.6

Homocysteine (HCY) ELISA Kit

20-abx156751
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat homocysteine ELISA kit

QY-E11727 96T
EUR 448.8

Homocysteine (Hcy) Assay Kit

abx294100-100g 100 µg Ask for price

Homocysteine (Hcy) Assay Kit

abx294100-20g 20 µg
EUR 650

Homocysteine (Hcy) Assay Kit

abx294100-50g 50 µg Ask for price

Homocysteine (HCY) ELISA Kit

abx156751-100g 100 µg
EUR 6412.5

Homocysteine (HCY) ELISA Kit

abx156751-10g 10 µg
EUR 712.5

Homocysteine (HCY) ELISA Kit

abx156751-50g 50 µg
EUR 3387.5

Homocysteine (HCY) ELISA Kit

abx576699-296tests 2 × 96 tests
EUR 687.5

Goat Homocysteine ELISA kit

E01A48781 96T
EUR 700
Description: ELISA

Goat Homocysteine ELISA kit

E06H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Homocysteine ELISA kit

E06H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Homocysteine ELISA kit

E06H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Sheep Homocysteine ELISA kit

E01A101074 96T
EUR 700
Description: ELISA

Human Homocysteine ELISA kit

E01A5119 96T
EUR 700
Description: ELISA

Mouse Homocysteine ELISA kit

E03H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Homocysteine ELISA kit

E03H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Homocysteine ELISA kit

E03H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Homocysteine ELISA kit

E01H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Homocysteine ELISA kit

E01H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Homocysteine ELISA kit

E01H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Homocysteine ELISA kit

E01A22613 96T
EUR 700
Description: ELISA

Canine Homocysteine ELISA kit

E01A66212 96T
EUR 700
Description: ELISA

Rabbit Homocysteine ELISA kit

E01A31349 96T
EUR 700
Description: ELISA

Monkey Homocysteine ELISA kit

E01A74928 96T
EUR 700
Description: ELISA

Bovine Homocysteine ELISA kit

E01A83646 96T
EUR 700
Description: ELISA

Monkey Homocysteine ELISA kit

E09H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Homocysteine ELISA kit

E09H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Homocysteine ELISA kit

E09H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Homocysteine ELISA kit

E04H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Homocysteine ELISA kit

E04H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Homocysteine ELISA kit

E04H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

S-Adenosyl Homocysteine [OVA]

DAG-WT855O 1 mg
EUR 520
Description: Synthetic

Porcine Homocysteine ELISA kit

E01A57499 96T
EUR 700
Description: ELISA

Chicken Homocysteine ELISA kit

E01A92368 96T
EUR 700
Description: ELISA

Rat HCY(Homocysteine) ELISA Kit

ER1509 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Rattus;Sensitivity: 4.688pmol/ml

Rat Homocysteine (HCY) Elisa kit

EK720387 96 Wells
EUR 0.56

Rat HCY(Homocysteine) ELISA Kit

EKF57965-48T 48T
EUR 396.9

Rat HCY(Homocysteine) ELISA Kit

EKF57965-5x96T 5x96T
EUR 2693.25

Rat HCY(Homocysteine) ELISA Kit

EKF57965-96T 96T
EUR 567

Rat Homocysteine(Hcy)ELISA Kit

EKC39199-48T 48T
EUR 597.24

Rat Homocysteine(Hcy)ELISA Kit

EKC39199-5x96T 5x96T
EUR 4052.7

Rat Homocysteine(Hcy)ELISA Kit

EKC39199-96T 96T
EUR 853.2

Rat Homocysteine (HCY) ELISA Kit

EK11899 96Т
EUR 799

ELISA Kit for Homocysteine (HCy)

CED984Ge 96Т
EUR 816

Rat Homocysteine, Hcy ELISA Kit

CELI-66076r 96 Tests
EUR 1063.2

Rat Homocysteine(Hcy)ELISA Kit

CSB-E13376r-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat Homocysteine (Hcy) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Homocysteine(Hcy)ELISA Kit

1-CSB-E13376r
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  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Homocysteine(Hcy) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Homocysteine (HCY) ELISA Kit

AE62777RA-48Tests 48 Tests
EUR 360
Description: Rat (Rattus norvegicus)

Rat Homocysteine (HCY) ELISA Kit

AE62777RA-96Tests 96 Tests
EUR 680
Description: Rat (Rattus norvegicus)

Rat Homocysteine(Hcy)ELISA Kit

NSL1441r 96 Tests
EUR 498

Rat Homocysteine(HCY) ELISA Kit

SL1283Ra -
EUR 498

Rat Homocysteine,Hcy ELISA Kit

YLA0300RA-48T 48T Ask for price

Rat Homocysteine,Hcy ELISA Kit

YLA0300RA-96T 96T Ask for price

BSA Conjugated Homocysteine (HCy)

CPD984Ge11 10ug
EUR 152

BSA Conjugated Homocysteine (HCy)

4-CPD984Ge11
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  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pan-species Homocysteine expressed in: chemical synthesis

OVA Conjugated Homocysteine (HCy)

CPD984Ge21 10ug
EUR 152

OVA Conjugated Homocysteine (HCy)

4-CPD984Ge21
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  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Pan-species Homocysteine expressed in: chemical synthesis

BSA Conjugated Homocysteine (HCy)

RPU51279-100ug 100ug
EUR 468.6

BSA Conjugated Homocysteine (HCy)

RPU51279-1mg 1mg
EUR 2074.8

BSA Conjugated Homocysteine (HCy)

RPU51279-50ug 50ug
EUR 364.8

OVA Conjugated Homocysteine (HCy)

RPU51280-100ug 100ug
EUR 468.6

OVA Conjugated Homocysteine (HCy)

RPU51280-1mg 1mg
EUR 2074.8

OVA Conjugated Homocysteine (HCy)

RPU51280-50ug 50ug
EUR 364.8

Goat Homocysteine(Hcy) ELISA Kit

NSL0646Gt 96T
EUR 528

Homocysteine-cysteine Disulfide

H616005 10mg
EUR 1108
Description: 4985-47-1

Homocysteine ELISA Kit (OKEH02557)

OKEH02557 96 Wells
EUR 934.8
Description: Description of target: Homocysteine is a non-protein amino acid with the formula HSCH2CH2CH(NH2)CO2H. It is a homologue of the amino acid cysteine, differing by an additional methylene (-CH2-) group. It is biosynthesized from methionine by the removal of its terminal Cε methyl group. Homocysteine can be recycled into methionine or converted into cysteine with the aid of B-vitamins. While detection of high levels of homocysteine has been linked to cardiovascular disease, lowering homocysteine levels may not improve outcomes.;Species reactivity: All;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.38 ng/mL

Mouse HCy(Homocysteine) ELISA Kit

ELK8718-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Mouse HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse HCy(Homocysteine) ELISA Kit

ELK8718-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Mouse HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

Human HCy(Homocysteine) ELISA Kit

ELK8987-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

Human HCy(Homocysteine) ELISA Kit

ELK8987-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human HCy protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HCy. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human HCy in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse HCY(Homocysteine) ELISA Kit

EM1109 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 4.688pmol/ml

Human Homocysteine(HCY)ELISA Kit

EKC34070-48T 48T
EUR 597.24

Human Homocysteine(HCY)ELISA Kit

EKC34070-5x96T 5x96T
EUR 4052.7

Human Homocysteine(HCY)ELISA Kit

EKC34070-96T 96T
EUR 853.2

Sheep Homocysteine (HCY) Elisa Kit

EK770229 96 Wells
EUR 0.97

Human Homocysteine (HCY) Elisa kit

EK716111 96 Wells
EUR 0.52

SAH (S adenosine L homocysteine)

E62K002 100ug
EUR 225

Human HCY(Homocysteine) ELISA Kit

EKF58017-48T 48T
EUR 396.9

Human HCY(Homocysteine) ELISA Kit

EKF58017-5x96T 5x96T
EUR 2693.25

Human HCY(Homocysteine) ELISA Kit

EKF58017-96T 96T
EUR 567

Mouse Homocysteine(HCY)ELISA Kit

EKC37068-48T 48T
EUR 535.99

Mouse Homocysteine(HCY)ELISA Kit

EKC37068-5x96T 5x96T
EUR 3637.08

Mouse Homocysteine(HCY)ELISA Kit

EKC37068-96T 96T
EUR 765.7

Mouse HCY(Homocysteine) ELISA Kit

EKF59110-48T 48T
EUR 396.9

Mouse HCY(Homocysteine) ELISA Kit

EKF59110-5x96T 5x96T
EUR 2693.25

Mouse HCY(Homocysteine) ELISA Kit

EKF59110-96T 96T
EUR 567

Mouse Homocysteine (HCY) ELISA Kit

EK11893 96Т
EUR 799

Human Homocysteine (HCY) ELISA Kit

EK11900 96Т
EUR 799

Human HCY(Homocysteine) ELISA Kit

EH4011 96T
EUR 628.92
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 4.688pmol/ml

Human Homocysteine, Hcy ELISA Kit

CELI-66076h 96 Tests
EUR 988.8

Mouse Homocysteine, Hcy ELISA Kit

CELI-66076m 96 Tests
EUR 1038

Human Homocysteine(HCY)ELISA Kit

CSB-E13814h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Homocysteine (HCY) in samples from serum, plasma, urine, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Homocysteine(HCY)ELISA Kit

1-CSB-E13814h
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  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Homocysteine(HCY) in samples from serum, plasma, urine, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Homocysteine(HCY)ELISA Kit

CSB-E16551m-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Mouse Homocysteine (HCY) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Homocysteine(HCY)ELISA Kit

1-CSB-E16551m
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  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Mouse Homocysteine(HCY) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Homocysteine (HCY) ELISA Kit

AE62770MO-48Tests 48 Tests
EUR 325
Description: Mouse (Mus musculus)

Mouse Homocysteine (HCY) ELISA Kit

AE62770MO-96Tests 96 Tests
EUR 610
Description: Mouse (Mus musculus)

Human Homocysteine (HCY) ELISA Kit

AE62778HU-48Tests 48 Tests
EUR 360
Description: Human (Homo sapiens)

Human Homocysteine (HCY) ELISA Kit

AE62778HU-96Tests 96 Tests
EUR 680
Description: Human (Homo sapiens)

Mouse Homocysteine(HCY) Elisa Kit

QY-E21697 96T
EUR 448.8

Human Homocysteine (HCY) ELISA Kit

KTE62507-48T 48T
EUR 359
Description: Human Homocysteine (HCY) ELISA Kit employs a two-site sandwich ELISA to quantitate Homocysteine in samples.

Human Homocysteine (HCY) ELISA Kit

KTE62507-96T 96T
EUR 619
Description: Human Homocysteine (HCY) ELISA Kit employs a two-site sandwich ELISA to quantitate Homocysteine in samples.

Human Homocysteine (HCY) ELISA Kit

KTE62507-96T5 96 T×5
EUR 2809
Description: Human Homocysteine (HCY) ELISA Kit employs a two-site sandwich ELISA to quantitate Homocysteine in samples.

Human Homocysteine (HCY) ELISA Kit

KTE62507-96T50 96 T×50
EUR 26209
Description: Human Homocysteine (HCY) ELISA Kit employs a two-site sandwich ELISA to quantitate Homocysteine in samples.

Mouse Homocysteine(Hcy) ELISA Kit

NSL1511m 96 Test
EUR 528

Human Homocysteine(Hcy)  ELISA Kit

NSL2020Hu 96 wells
EUR 468

Human Homocysteine(HCY)ELISA Kit

SL2047Hu 96 Tests
EUR 468

Human Homocysteine,Hcy ELISA Kit

YLA0647HU-48T 48T Ask for price

Human Homocysteine,Hcy ELISA Kit

YLA0647HU-96T 96T Ask for price

Mouse Homocysteine,Hcy ELISA Kit

YLA0120MO-48T 48T Ask for price

Mouse Homocysteine,Hcy ELISA Kit

YLA0120MO-96T 96T Ask for price

Guinea Pig Homocysteine ELISA kit

E01A40062 96T
EUR 700
Description: ELISA

Guinea pig Homocysteine ELISA kit

E05H0396-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Homocysteine ELISA kit

E05H0396-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Homocysteine ELISA kit

E05H0396-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Homocysteine in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Canine Homocysteine (HCY) Elisa kit

EK762301 96 Wells
EUR 0.95

Bovine Homocysteine, Hcy ELISA Kit

CELI-66076b 96 Tests
EUR 1113.6

Canine Homocysteine, Hcy ELISA Kit

CELI-66076d 96 Tests
EUR 1113.6

Rabbit Homocysteine, Hcy ELISA Kit

CELI-66076Rb 96 Tests
EUR 1113.6

Bovine Homocysteine(Hcy) ELISA Kit

NSL0357Bo 96 T
EUR 528

Canine Homocysteine(Hcy) ELISA Kit

NSL0435Ca 530 wells
EUR 528

Bovine Homocysteine,Hcy ELISA Kit

YLA0397BO-48T 48T Ask for price

Bovine Homocysteine,Hcy ELISA Kit

YLA0397BO-96T 96T Ask for price

Canine Homocysteine(HCY)ELISA Kit

YLA0053CA-48T 48T Ask for price

Canine Homocysteine(HCY)ELISA Kit

YLA0053CA-96T 96T Ask for price

General Hcy/ Homocysteine ELISA Kit

E0037Ge 1 Kit
EUR 630

General Homocysteine (HCy) ELISA Kit

DLR-HCy-Ge 96T
EUR 533
Description: serum, plasma, tissue homogenates or other biological fluids.

General Homocysteine, Hcy ELISA KIT

ELI-02638Ge 96 Tests
EUR 1063.2

General Homocysteine (HCy) ELISA Kit

DL-HCy-Ge 96T
EUR 507
Description: serum, plasma, tissue homogenates or other biological fluids.

General Homocysteine (HCy) ELISA Kit

CED984Ge-10x96wellstestplate 10x96-wells test plate
EUR 6588.86
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Homocysteine (HCy) in serum, plasma and other biological fluids.

General Homocysteine (HCy) ELISA Kit

CED984Ge-1x48wellstestplate 1x48-wells test plate
EUR 647.78
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Homocysteine (HCy) in serum, plasma and other biological fluids.

General Homocysteine (HCy) ELISA Kit

CED984Ge-1x96wellstestplate 1x96-wells test plate
EUR 873.98
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Homocysteine (HCy) in serum, plasma and other biological fluids.

General Homocysteine (HCy) ELISA Kit

CED984Ge-5x96wellstestplate 5x96-wells test plate
EUR 3572.93
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of General Homocysteine (HCy) in serum, plasma and other biological fluids.

General Homocysteine (HCy) ELISA Kit

4-CED984Ge
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of General Homocysteine (HCy) in samples from serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species.
Physique mass index (BMI) was positively related and hemoglobin A1c (HbA1c) ranges, excessive density lipoprotein ldl cholesterol (HDL-C) ranges and the presence of stroke had been negatively related to serum uric acid ranges in male sufferers. In distinction, solely LVEF was positively related to uric acid ranges in females. In conclusion, homocysteine stage is an impartial threat issue related to serum creatinine and BUN ranges in male sufferers with hypertension.